By a GenomeWeb staff reporter

NEW YORK (GenomeWeb News) – Horizon Discover today said it is collaborating with the Rosalind Franklin University of Medical Sciences to develop a human cellular disease model of cystic fibrosis.

The deal covers use of Horizon's Genesis precision genome editing technology to "reconstitute a specific mutation" in the cystic fibrosis transmembrane conductance regulator, or CFTR, protein in the endogenous genome of a lung cancer cell line.

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The new Riken president outlines some of his plans for the institute.

The Guardian discusses whether big science projects are worth the loss of resources available for other scientific pursuits.

An NEJM update from the ClinVar team highlights the difficulties of interpreting genetic variants.

In Nature this week: genomic analysis of high-grade serous ovarian cancer, and more.