NEW YORK (GenomeWeb News) - Howard Hughes Medical Institute warned it could make additional budget cuts above those carried out in the year ending Aug. 31, after ending the fiscal year with a $3.5 billion, or 20 percent, drop in its endowment, according to its 2009 Annual Report — the first time the institute has published its full yearly report on the Internet.

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In Nature this week: Icelandic genome sequences, approach to increase CRISPR efficiency, and more.

Testing showing "genetic incompatibilities" have led thousands of couples in Saudi Arabia to call off their weddings, the BBC reports.

Decode Genetics' ability to tell Icelanders, even ones the company hasn't sequenced, about their disease risk brings up ethical questions.

Genetic analysis of Britain's King Richard III and modern descendants of his relatives indicate breaks in the male line.