Here's something that will make you long for the good old days: five years ago, getting grant funding seemed like a major challenge. In our May 2004 issue of Genome Technology — just after then-NIH Director Elias Zerhouni had succeeded in doubling the agency's budget — we devoted our cover story to offering advice on writing and winning grants, and we profiled a number of program directors who could offer their assistance to readers.

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In PNAS this week: transcript patterns in drug-resistant cancer cells, function of high-altitude adaption gene, and more.

Monitoring gene expression changes could help sniff out athletes using performance-enhancing drugs, New Scientist says.

The University of Southern California lodges a cross-complaint in its legal dispute with the University of California, San Diego, over a large Alzheimer's disease project.

In PLOS this week: gene fusion in premature ovarian failure, population patterns in the Franciscana dolphin, and more.