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Global Vaccine Approach

The director-general of the World Health Organization has called for an end to "vaccine nationalism," NPR reports.

In a briefing yesterday, WHO Director-General Tedros Adhanom Ghebreyesus instead urged nations to join a global vaccine agreement called the COVAX Global Vaccines Facility, which would enable global sharing of COVID-19 vaccines. "The fastest way to end this pandemic and to reopen economies is to start by protecting the highest risk populations everywhere," Tedros said at the briefing, according to New Scientist.

This call, NPR notes, comes as the European Union, US, UK, and Switzerland have struck deals with vaccine makers for access to candidate vaccines. Tedros said he was concerned that "vaccine nationalism" would lead to some countries stockpiling vaccines, leaving others with limited access to vaccines, noting that this occurred in the early days of the pandemic with protective gear. "Nationalism exacerbated the pandemic and contributed to the total failure of the global supply chain," he said, according to NPR.

NPR adds the deadline to set the terms of the new agreement is at the end of the month.

The Scan

Myotonic Dystrophy Repeat Detected in Family Genome Sequencing Analysis

While sequencing individuals from a multi-generation family, researchers identified a myotonic dystrophy type 2-related short tandem repeat in the European Journal of Human Genetics.

TB Resistance Insights Gleaned From Genome Sequence, Antimicrobial Response Assays

Researchers in PLOS Biology explore M. tuberculosis resistance with a combination of sequencing and assays looking at the minimum inhibitory concentrations of 13 drugs.

Mendelian Disease Genes Prioritized Using Tissue-Specific Expression Clues

Mendelian gene candidates could be flagged for further functional analyses based on tissue-specific transcriptome and proteome profiles, a new Journal of Human Genetics paper says.

Single-Cell Sequencing Points to Embryo Mosaicism

Mosaicism may affect preimplantation genetic tests for aneuploidy, a single-cell sequencing-based analysis of almost three dozen embryos in PLOS Genetics finds.