Genome Biology Papers on Cancer Drug Resistance, Breast Cancer TWAS, Beijing Air Microbes

Mar 04, 2020

Australian researchers report on findings from a functional analysis of cancer drug resistance genes in cell lines and tumor xenograft models in mice. Using a CRISPR-Cas9 gene editing-based knockout screening in cancer cells, the team tallied the genes and pathways targeted by cancer treatments, while unearthing 10 genes related to resistance to multiple drugs.

To read the full story....

...and receive Daily News bulletins.

Already have a GenomeWeb or 360Dx account?
Login Now.

Don't have a GenomeWeb or 360Dx account?
Register for Free.

Breaking News

Recent Headlines from
Precision Oncology News

The Scan

Keep It (Partly) Virtual

A survey by Nature finds that most researchers want scientific meetings to continue virtually or with a virtual component, even after the pandemic ends.

For Cross-Protection

Bloomberg reports that the B.1.351 SARS-CoV-2 viral variant could prompt the formulation of better vaccines.

Proteomics of Severity

Certain blood proteins may be able to distinguish COVID-19 patients who will become critically ill from those who will not, the Atlanta Journal-Constitution reports.

Genome Biology Papers on Regulatory Element, Single-Cell Integration, Sequence Simulation Tools

In Genome Biology this week: algorithm to assess regulatory features, approach to integrate multiple single-cell RNA-seq datasets, and more.

Featured White Papers

Compatibility of Liquid Biopsy Assays on Multiple Sequencing Platforms

CAS-CLOVER The clean alternative to CRISPR/Cas9 for gene editing in the drug discovery and development industry

Mar

09

Featured Webinar

Implementation of Whole-Exome and Virtual Panel Testing for Rare Disease at a Children’s Hospital

The growth of next-generation sequencing (NGS) testing presents both opportunities and challenges for clinical, informatics, and laboratory teams.

Mar

11

Featured Webinar

Virtual Molecular Tumor Board Series: Gene Fusions as Druggable Targets

In this session, the third in the Precision Oncology News Virtual Molecular Tumor Board Series, our expert panelists will review patient cases in which genomic profiling has identified gene fusions that may or may not serve as druggable targets.

Mar

24

Featured Webinar

Single-Cell Analysis and Genome Editing in Preclinical Disease Modeling: Detailed Insights into Leukemia Lineage

This webinar, the first in a “Women in Single Cell” series sponsored by Mission Bio, will discuss the use of single-cell analysis to assess genome editing for use in pre-clinical disease modeling.

Apr

23

Featured Webinar

Advances in Single-Cell Proteomics: Building a Complete Picture of Cellular Identity

Recent advances in single-cell technologies have provided unprecedented -omic-level insights into cellular heterogeneity and function.

Menu