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NEW YORK — By focusing on a founder population with reduced genetic heterogeneity, researchers have uncovered rare genetic variants in the protocadherin gene that contribute to schizophrenia risk.

Schizophrenia, which is marked by delusion, hallucinations, and disorganized thoughts, affects about 1 percent of the global population. While studies have suggested that schizophrenia is highly heritable, genome-wide association studies have only uncovered common variants that together account for about a third of schizophrenia heritability.

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Nature News writes that viral genomic surveillance in the US faces systemic issues.

President Joe Biden is seeking an increase in federal spending, including higher budgets for the National Institutes of Health and Centers for Disease Control and Prevention.

A small, early-stage trial of a combination therapy for brain cancer reports favorable responses in two patients, according to the Guardian.

In PLOS this week: sex-stratified genome-wide association study of chronic pain, sequencing data from Indigenous Mexican groups, and more.

Apr
21
Sponsored by
Mission Bio

This webinar, the first in a “Meet the Authors” series sponsored by Mission Bio, will discuss the application of single-cell analysis to decipher clonal evolution across several stages of disease development in myeloid malignancies.