NEW YORK – A team of US researchers has leveraged transcriptomics data sets to identify existing drugs that may help treat COVID-19.
First, researchers in Marina Sirota's lab at the University of California, San Francisco obtained gene expression profiles, including up- and downregulated genes, from three studies of human cells infected with SARS-CoV-2. Then, they compared them to publicly available datasets of drug-induced gene expression in cultured human cells.