NEW YORK (GenomeWeb) – Scientists have used whole-exome sequencing to detail the genomic changes that drove relapse in patients with acute lymphoblastic leukemia (ALL).

Cancers such as leukemia are not a homogeneous disease, but a jumble of different dividing cancer cells, called clones, with distinctive sets of mutations. While chemotherapy might kill almost all the clones, some might escape therapy, leaving them to multiply and cause relapse.

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The US Food and Drug Administration has new guidelines that enable some gene and cell therapies to undergo expedited review, according to the New York Times.

Using gene drives to control invasive species might be too risky, an initial advocate of the approach says.

Researchers have grown tumors in 3D cell cultures to better understand cancer, the Economist reports.

In Science this week: intellectual property experts argue patent battles such as the one over CRISPR are wasteful, and more.