NEW YORK (GenomeWeb) – Scientists from the UK have exploited single nucleotide polymorphisms in alleles that cause corneal dystrophy to edit the genes using CRISPR/Cas9.

While CRISPR/Cas9 genome editing can be programmed to target many sections of the genome, the technique will only make a double-stranded break if the guide RNA matches up next to a three-base-pair section called a protospacer adjacent motif (PAM). For Cas9 enzymes from Streptococcus pyogenes commonly used in genome editing applications, PAMs take the form of NGG.

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Researchers find that a personalized medicine approach could help people who experience pain while taking statins, New Scientist reports.

US National Science Foundation is continuing its responsible research conduct training policy despite its flaws, ScienceInsider reports.

A CRISPR-themed meeting explored how the tool could and should be used, Wired reports.

In Science this week: database of proteins' effects on cancer, targeted error correction sequencing, and more.

Sep
20
Sponsored by
Ion Torrent

This webinar will discuss how next-generation sequencing (NGS) can help clinical research labs and pathologists save time, money, and samples compared to single-analyte oncology research assays.