NEW YORK (GenomeWeb) – Scientists from the UK have exploited single nucleotide polymorphisms in alleles that cause corneal dystrophy to edit the genes using CRISPR/Cas9.

While CRISPR/Cas9 genome editing can be programmed to target many sections of the genome, the technique will only make a double-stranded break if the guide RNA matches up next to a three-base-pair section called a protospacer adjacent motif (PAM). For Cas9 enzymes from Streptococcus pyogenes commonly used in genome editing applications, PAMs take the form of NGG.

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The Washington Post reports on a Federal Bureau of Investigation plan to place rapid DNA analyzers at booking stations around the country.

In an editorial, officials from scientific societies in the US and China call for the international community to develop criteria and standards for human germline editing.

The US National Institutes of Health is to review studies that have received private support for conflicts of interest, according to the New York Times.

In Science this week: the PsychENCODE Consortium reports on the molecular mechanisms of neuropsychiatric disorders, and more.