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NEW YORK (GenomeWeb) – An international team of researchers has connected rare coding variants in three microglial-expressed genes to Alzheimer's disease risk.

While some 30 genetic loci have been associated with risk of developing late-onset Alzheimer's disease, those loci only explain a portion of disease risk. To uncover rare variants that may also contribute to Alzheimer's disease risk, researchers led by the University of Pennsylvania's Gerard Schellenberg conducted a three-stage case-control study drawing on data from more than 85,000 people.

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The Wall Street Journal looks into FamilyTreeDNA's handling of genetic genealogy searches by law enforcement.

In a point-counterpoint in the Boston Globe, researchers discuss the potential of gene editing to prevent Lyme disease, but also the pitfalls of doing so.

MIT's Technology Review reports that researchers hope to develop a CRISPR-based pain therapy.

In Science this week: atlas of malaria parasites' gene expression across their life cycles, and more.

Aug
28
Sponsored by
Horizon Discovery

This webinar will provide an overview of alternatives to the popular Cas9 nuclease used in CRISPR gene editing.

Oct
23
Sponsored by
Swift Biosciences

This webinar will illustrate how single-cell methylation sequencing can be applied to gain significant insight into epigenetic heterogeneity in disease states, advancing cancer research discoveries. 

Oct
24
Sponsored by
Sunquest

This webinar will tell the story of Versiti’s journey in transforming genetic testing from a manual to a digitized process. It will include detail on how the organization succeeded, pain points along the way, a novel approach to variant assessment, and future plans for the program.