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NEW YORK (GenomeWeb) – A rare loss-of-function mutation found among Old Order Amish individuals protects against some of the effects of aging, a new study has found.

The mutation, located in the SERPINE1 gene, affects the function of plasminogen activator inhibitor-1 (PAI-1), which has a role in cellular senescence and is expressed at higher levels in senescent cells, leading the researchers to suspect that variants in this gene could influence aging and cardiometabolic disease, which affect lifespan.

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Nature survey finds a high level of support among scientists for former Vice President Joe Biden in the upcoming US election.

Two coronavirus vaccine trials that had been paused in the US have resumed.

The Scientist reports the physician behind Surgisphere inactivated his medical license in one state and received one in another.

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