NEW YORK – Researchers have devised an approach that might make polygenic scores useful for people from mixed ancestral backgrounds.
Polygenic scores can be used to predict a person's likelihood of developing a trait or disease, but they are often not able to make such predictions outside of the ancestry group in which they were developed. This is a particular problem for people from recently admixed populations like African Americans, Afro Caribbeans, Central and Southern Americans, and Ethiopians and North Africans.