NEW YORK (GenomeWeb) – An international research team, led by the University of Cambridge, has discovered 15 new risk loci for coronary artery disease (CAD).

The study, published today in Nature Genetics, adds to the 58 known risk loci for the disease and sheds light on the mechanisms responsible for disease progression. These 15 new risk loci bring the total number of known risk loci associated with CAD to 73.

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The UK's Nuffield Council on Bioethics says genetically modifying human embryos could be morally permissible, according to the Guardian.

A new Nature Biotechnology paper reports that CRISPR-Cas9 gene editing can lead to large deletions or complex rearrangements that could be pathogenic.

The Wall Street Journal likens a prototype developed by Synthetic Genomics to a "biological fax machine."

In PNAS this week: strategy for reactivating Rett syndrome-linked MECP2, small molecules able to suppress Staphylococcus aureus virulence, and more.