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NEW YORK (GenomeWeb) – A loss-of-function variant in a gene involved in inflammatory processes appears to protect against the development of nasal polyps and chronic rhinosinusitis, according to a new set of genome-wide association studies.

While nasal polyps are not malignant, they can cause nasal obstructions, runny nose, and postnasal drip. They are also a risk factor for chronic rhinosinusitis, or inflamed sinuses, which often occurs in combination with asthma.

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