NEW YORK (GenomeWeb) – A genome-wide analysis has linked hundreds of genetic loci — including nearly six dozen novel ones — to intraocular pressure, a key risk factor for primary open-angle glaucoma.

Primary open-angle glaucoma affects nearly 3 million adults in the US and often has no warning symptoms, according to the American Academy of Ophthalmology. But, as people's intraocular pressures increases, so does their risk of developing glaucoma.

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