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NEW YORK (GenomeWeb) – Researchers have uncovered a common genetic variant that is associated with liver injury in multiple sclerosis patients who have been treated with interferon-β, suggesting a new way to pick out patients at risk of the adverse reaction.

IFN-βs are the most commonly used treatments for multiple sclerosis, but up to 60 percent of patients given the drug develop abnormal biochemical liver test results and 2 percent experience drug-induced liver injury.

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Stephen Hahn, the nominee to lead the US Food and Drug Administration, underwent a Senate confirmation hearing yesterday, the Washington Post reports.

The US Food and Drug Administration has approved an RNA interference drug to treat acute hepatic porphyria.

Gizmodo looks over the past decade of consumer DNA testing to find the field to be lacking.

In Nature this week: native RNA sequencing and analysis of a human poly(A) transcriptome, nanopore sequencing-based method to analyze short tandem repeat expansions, and more.

Dec
02
Sponsored by
Sophia Genetics

This webinar will discuss how Moffitt Cancer Center has implemented a new capture-based application to accurately assess myeloid malignancies by detecting complex variants in challenging genes in a single experiment.  

Dec
04
Sponsored by
BC Platforms

This webinar will discuss what it takes to begin realizing precision medicine in a comprehensive clinical infrastructure, with insights from the Colorado Center for Personalized Medicine (CCPM).