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NEW YORK (GenomeWeb) – Both genetic and environmental factors influence imprinting at a differentially methylated noncoding RNA gene, according to a new study.

Genomic imprinting, a type of allele-specific DNA methylation, is typically thought to be determined by parental origin. But, previous work found a unique pattern of DNA methylation at the noncoding nc886 gene: it exhibited allele-specific DNA methylation in about 75 percent of people, but is unmethylated in about 25 percent of people.

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In Science this week: influence of the nuclear genome on human mitochondrial DNA, and more.