NEW YORK — Researchers have developed a new screening tool to home in on genetic variants that contribute to disease risk, which they applied to study the genetic factors influencing lupus.
Systemic lupus erythematosus (SLE) affects about 300,000 people in the US, the majority of whom are women. Previous studies have implicated both genetic and environmental contributors to the condition. While nearly 100 genetic loci have been associated with lupus, it is also closely tied to previous infection with Epstein-Barr virus.