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NEW YORK (GenomeWeb) – The Alzheimer's disease risk variant APOE4 leads to a number of changes within brain cells, including differences in gene expression, according to a new study.

People with the apolipoprotein E4 variant have a higher risk of developing late-onset Alzheimer's disease — the variant is three times more common among people with the condition than the general public. But while APOE4 has clearly been linked to higher levels of the amyloid protein that forms plaques seen in patients' brains, it's been unclear how this increase takes place.

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Three genetic testing companies form a coalition to influence how Congress considers genetic privacy, The Hill reports.

University of California, San Diego researchers investigate how skin care products influence the skin microbiome, Scientific American reports.

The Wall Street Journal examines billing codes used by uBiome.

In PNAS this week: links between lung adenocarcinoma and lncRNA, algorithm to impute and cluster Hi-C interaction profiles from single cells, and more.

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This webinar will discuss how the Molecular Pathology Laboratory at the University of Oklahoma (OUMP) is using a new quality improvement model to support molecular testing of oncology patients. 

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Mission Bio

This webinar will outline a project that performs large-scale and integrative single-cell genome and transcriptome profiling of pediatric acute lymphoblastic leukemia (ALL) cases at diagnosis, during drug treatment, and in case of relapse.