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NEW YORK (GenomeWeb) – Researchers in China have discovered a protein that regulates the uptake of dietary cholesterol in the gut, and which might serve as a drug target to keep blood cholesterol levels in check and prevent heart disease.

A truncated version of the protein, called LIMA1, has led to unusually low levels of low-density lipoprotein cholesterol (LDL-C) and reduced cholesterol absorption in a family of Chinese Kazahks, the researchers found, and additional experiments in mice further explored the molecular role of LIMA1.

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Matt Hancock, the UK health secretary, is calling for the swift rollout of predictive genetic tests, the Guardian reports.

A WHO panel is calling for a global registry of human germline gene-editing projects, according to Stat News.

Vox writes that lab mishaps involving pathogens are quite common.

In Genome Biology this week: analysis of wild and cultivated peach genomes, Hi-C-based pipeline for assembling microbial genomes from metagenomic data, and more.

Apr
11
Sponsored by
Bionano Genomics

This webinar will review a recent study that applied whole-genome sequencing and optical genome mapping to identify a large number of previously undetected somatic structural variants in leukemia samples.