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Home » Tools & Technology » Gene Silencing/Gene Editing » CRISPR Screening Approach for Mapping Genetic Interactions Uncovers Masked Phenotypes

CRISPR Screening Approach for Mapping Genetic Interactions Uncovers Masked Phenotypes

Mar 18, 2020
|
staff reporter

NEW YORK – A team led by researchers at the University of Toronto has developed a CRISPR-based screening system that multiplexes Cas9 and Cas12a, which they've used to systemically map genetic interactions and interrogate the functions of large genomic segments in mammalian cells.

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