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NEW YORK (GenomeWeb) – A common allele in the FGF21 gene affects the macronutrients people tend to eat and is associated with lower body fat, but high blood pressure.

FGF21 is a hormone secreted by the liver that sends a signal to the brain to suppress sugar and alcohol consumption, while also stimulating glucose uptake and acting as an insulin sensitizer. Because of this, it has been pursued as the basis of obesity and type 2 diabetes treatments.

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