Genetic Research
News on genetic research, including genome-wide association studies, genotyping, metagenomics, basic research in genetics, genomics, and molecular diagnostics.
Reproduction, Lifespan Show Antagonistic Pleiotropy in Genetic Analysis
Using UK Biobank data, researchers found that genetic variants linked to increased reproductive capabilities coincided with shorter lifespan in individuals of European ancestry.
Organ-Specific Aging Markers Picked Out of Plasma Proteomic Analysis
With these markers, researchers established models for looking at aging across 11 human organs, highlighting ties between accelerated organ aging and disease.
Germline Mutagenesis Traced Back to Meiotic Breaks, Error-Prone Repair
By mapping mutations in relation to recombination hotspots, researchers revealed mutagenic effects of meiotic DNA breaks and error-prone repair mechanisms.
White Adipose Tissue Proteins Linked to Diabetes, Exercise Training in Proteomics Study
Researchers highlighted diabetes- or weight-related white adipose tissue signatures, and searched for adipose tissue proteomic shifts after an eight-week exercise intervention.
The resource contains Illumina whole-genome sequencing data from UK Biobank participants and is available to approved researchers worldwide.