Genetic Research

News on genome-wide association studies, genotyping, metagenomics, basic research in genetics, genomics, and molecular diagnostics.

In analyses of multiple traits and diseases, investigators uncovered loss-of-function or truncating changes with apparent protective effects.

Scientists have sequenced more than 2,700 distinct strains from the National Collection of Type Cultures, a non-profit biorepository run by Public Health England.

The two studies used Drop-seq RNA profiling to discover essentially all cell types and establish cell lineages in a model organism flatworm. 

St. Jude researchers found germline mutations in the transcription factor gene IKZF1 in 0.9 percent of presumed sporadic pediatric acute lymphoblastic leukemia cases.

The team used genetic scoring to identify infants without a family history of the disease who had more than a 10 percent risk for developing islet antibodies.

What happens to scientific papers when certain journals are no longer published? Some scientists are trying to make sure they don't disappear forever.

A study in Microbiome finds that heavy drinkers have an unhealthy mix of bacteria in their mouths.

Doctors and patients are still trying to figure out what role at-home genetic testing should play in healthcare, Newsweek says.

In Genome Research this week, mismatch repair deficiency in C. elegans, retracing transcriptions start site evolution in the human genome, and more.