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NEW YORK (GenomeWeb) – Scientists from the University of California, San Diego and UC-Irvine have created a proof-of-concept, CRISPR/Cas9-based gene drive to genetically modify entire populations of the malaria-carrying mosquito Anopheles stephensi.

Led by co-first authors Valentino Gantz of UCSD and Nijole Jasinskiene of UC-Irvine, and senior authors Ethan Bier and Anthony James of UC-Irvine, the scientists adapted a mutagenic chain reaction gene drive to spread genes conferring resistance to the malaria parasite Plasmodium falciparum.

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In PLOS this week: gene variant may protect against trypanosomiasis, GLIS3 role in type 2 diabetes, and more.

Aug
28
Sponsored by
Horizon Discovery

This webinar will provide an overview of alternatives to the popular Cas9 nuclease used in CRISPR gene editing.

Oct
23
Sponsored by
Swift Biosciences

This webinar will illustrate how single-cell methylation sequencing can be applied to gain significant insight into epigenetic heterogeneity in disease states, advancing cancer research discoveries.