Skip to main content
Premium Trial:

Request an Annual Quote

Santaris, Miragen Expand microRNA Partnership to Include Additional Targets

Premium

Santaris Pharma and Miragen Therapeutics this week announced that they have expanded their ongoing microRNA therapeutics partnership to include six additional targets.

The companies first began working together in 2010 when they signed a deal giving Miragen access to Santaris' locked nucleic acid technology to develop miRNA inhibitors against four unnamed cardiovascular disease targets (GSN 6/24/2010). As part of the arrangement, Santaris picked up an undisclosed stake in Miragen.

The newest agreement brings the number of targets against which Miragen can apply the LNA technology to ten. As with the first deal, Santaris received an upfront payment of cash and equity, and stands to receive payments based on the achievement of clinical milestones plus royalties on marketed products.

Additional terms were not disclosed.

The Scan

Y Chromosome Study Reveals Details on Timing of Human Settlement in Americas

A Y chromosome-based analysis suggests South America may have first been settled more than 18,000 years ago, according to a new PLOS One study.

New Insights Into TP53-Driven Cancer

Researchers examine in Nature how TP53 mutations arise and spark tumor development.

Mapping Single-Cell Genomic, Transcriptomic Landscapes of Colorectal Cancer

In Genome Medicine, researchers present a map of single-cell genomic and transcriptomic landscapes of primary and metastatic colorectal cancer.

Expanded Genetic Testing Uncovers Hereditary Cancer Risk in Significant Subset of Cancer Patients

In Genome Medicine, researchers found pathogenic or likely pathogenic hereditary cancer risk variants in close to 17 percent of the 17,523 patients profiled with expanded germline genetic testing.