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Rosetta Accepting FNA Samples for Analysis with miRNA Lung Cancer Diagnostic

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Rosetta Genomics this week announced that it has begun to accept fine-needle aspirate cell block samples for analysis using its miRview Squamous test, which uses microRNA signatures to differentiate squamous from non-squamous non-small-cell lung cancer.

"FNA is a less invasive method to obtain tumor cells compared with tumor resections or biopsies … [enabling] patients and physicians to benefit from a highly accurate diagnostic assay without having to undergo a more invasive procedure," the company said.

The Scan

Enzyme Involved in Lipid Metabolism Linked to Mutational Signatures

In Nature Genetics, a Wellcome Sanger Institute-led team found that APOBEC1 may contribute to the development of the SBS2 and SBS13 mutational signatures in the small intestine.

Family Genetic Risk Score Linked to Diagnostic Trajectory in Psychiatric Disorders

Researchers in JAMA Psychiatry find ties between high or low family genetic risk scores and diagnostic stability or change in four major psychiatric disorders over time.

Study Questions Existence of Fetal Microbiome

A study appearing in Nature this week suggests that the reported fetal microbiome might be the result of sample contamination.

Fruit Fly Study Explores Gut Microbiome Effects on Circadian Rhythm

With gut microbiome and gene expression experiments, researchers in PNAS see signs that the microbiome contributes to circadian rhythm synchronicity and stability in fruit flies.