Researchers Use CRISPR to Epigenetically Alter Disease Phenotypes in Mice

Dec 07, 2017

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NEW YORK (GenomeWeb) – A team led by researchers at the Salk Institute has developed a CRISPR-Cas9 genome editing system that epigenetically activates target genes without causing DNA double-strand breaks (DSBs). As they reported today in Cell, the investigators used the new system to treat diabetes, acute kidney disease, and muscular dystrophy in mouse models.

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