NEW YORK (GenomeWeb) – A team of researchers at the University of California, Berkeley has developed a tool that it says can facilitate the rapid evolution of biotechnologically useful phenotypes in cells.

As they wrote today in Nature, they created a system called EvolvR that can continuously diversify all nucleotides within a tunable window at user-defined loci by generating mutations using engineered DNA polymerases targeted via CRISPR-guided nickases.

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