NEW YORK (GenomeWeb) – A team of researchers at the University of California, Berkeley has developed a tool that it says can facilitate the rapid evolution of biotechnologically useful phenotypes in cells.

As they wrote today in Nature, they created a system called EvolvR that can continuously diversify all nucleotides within a tunable window at user-defined loci by generating mutations using engineered DNA polymerases targeted via CRISPR-guided nickases.

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British Nobel laureates and Fields Medal winners warn that a 'hard' Brexit could harm science across the UK, the Guardian reports.

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In PNAS this week: de novo NUS1 mutations linked to Parkinson's disease risk, candidate hepatocellular carcinoma drivers, and more.

Nov
05
Sponsored by
Sophia Genetics

With the Next Generation Sequencing (NGS), genomes sequencing has been democratized over the last decades with the detection of genomic alterations, thus replacing Sanger sequencing.

Nov
15
Sponsored by
Twist Bioscience

This webinar will discuss how Amyris, a biotechnology company that develops renewable products for a broad range of applications and industries, uses large-scale microbial engineering to support its manufacturing processes.

Dec
03
Sponsored by
Advanced Cell Diagnostics

This webinar will demonstrate how a research team at the National Institutes of Health evaluated a novel in situ hybridization approach and applied it to study splice variants related to schizophrenia.