NEW YORK (GenomeWeb) – A US-UK research team combined machine learning with a multiplexed single-guide RNA (sgRNA) expression strategy that promotes the functional ablation of single genes and allows for combinatorial targeting in a bid to design and construct a genome-wide, sequence-verified, arrayed CRISPR library.

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The US Food and Drug Administration has new guidelines that enable some gene and cell therapies to undergo expedited review, according to the New York Times.

Using gene drives to control invasive species might be too risky, an initial advocate of the approach says.

Researchers have grown tumors in 3D cell cultures to better understand cancer, the Economist reports.

In Science this week: intellectual property experts argue patent battles such as the one over CRISPR are wasteful, and more.