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Recent RNAi-Related Papers of Note: Feb 5, 2009

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Effective siRNA Targeting of the 3’ Untranslated Region of the West Nile Virus Genome

Antiviral Research, Jan. 7, 2008; epub ahead of print
Koski et al.


Post-Transcriptional Cross-Regulation Between Drosha and DGCR8

Cell, Jan. 9, 2009; 136: 1, 75-84
Kim et al.


A Single Anti-microRNA Antisense Oligodeoxyribonucleotide Targeting Multiple microRNAs Offers an Improved Approach for microRNA Interference

Nucleic Acids Research, Jan. 9, 2009; epub ahead of print
Yang et al.


miRNA In Situ Hybridization in Formaldehyde and EDC-Fixed Tissues

Nature Methods, Jan. 11, 2009; epub ahead of print
Tuschl et al.


Sustained Long-Term RNA Interference in Nucleus Pulposus Cells In Vivo Mediated by Unmodified Small Interfering RNA

European Spine Journal, Jan. 14, 2009; epub ahead of print
Doita et al.

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Discovery of Herpes B Virus-Encoded microRNAs

Journal of Virology, Jan. 14, 2009; epub ahead of print
Griffiths et al.


A Distinct Class of Small RNAs Arises from Pre-miRNA-Proximal Regions in a Simple Chordate

Nature Structural & Molecular Biology, Jan. 18, 2009; epub ahead of print
Haley et al.


RDE-1 Slicer Activity is Required Only for Passenger-Strand Cleavage During RNAi in Caenorhabditis elegans

Nature Structural & Molecular Biology, Jan. 18, 2009; epub ahead of print
Ketting et al.


Functional Links Between Clustered microRNAs: Suppression of Cell-Cycle Inhibitors by microRNA Clusters in Gastric Cancer

Nucleic Acids Research, Jan. 19, 2009; epub ahead of print
Kim et al.


Asymmetric Shorter-Duplex siRNA Structures Trigger Efficient Gene Silencing with Reduced Non-Specific Effects

Molecular Therapy, Jan. 20, 2009; epub ahead of print
Lee et al.

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Phosphorylation of FMRP Inhibits Association with Dicer

RNA, Jan. 20, 2009; epub ahead of print
Cheever & Ceman


The SID-1 Double-Stranded RNA Transporter is Not Selective for dsRNA Length

RNA, Jan. 20, 2009; epub ahead of print
Hunter et al.


Importin 8 is a Gene-Silencing Factor that Targets Argonaute Proteins to Distinct mRNAs

Cell, Jan. 21, 2009; epub ahead of print
Meister et al.


Controlling HBV Replication In Vivo by Intravenous Administration of Triggered Pegylated siRNA Nanoparticles

Molecular Pharmaceutics
, Jan. 21, 2009; epub ahead of print
Miller et al.


Polymorphic Mature microRNAs from Passanger Strand of Pre-miR-146a Contribute to Thyroid Cancer

Proceedings of the National Academy of Sciences, Jan. 21, 2008; epub ahead of print
de la Chapelle et al.


dsRNA with 5’ Overhangs Contributes to Endogenous and Antiviral RNA Silencing Pathways in Plants

EMBO Journal, Jan. 22, 2009; epub ahead of print
Fukunaga & Doudna

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Export of RNA Silencing from C. elegans Tissues Does Not Require the RNA Channel SID-1

Proceedings of the National Academy of Sciences, Jan. 23, 2009; epub ahead of print
Hunter et al.


microRNAs as Modulators of Smoking-Induced Gene Expression Changes in Human Airway Epithelium

Proceedings of the National Academy of Sciences, Jan. 23, 2009; epub ahead of print
Spira et al.


Genetic Analyses Reveal a Requirement for Dicer1 in the Mouse Urogenital Tract

Mammalian Genome
, Jan. 24, 2009; epub ahead of print
Greenfield et al.


RNAither, an Automated Pipeline for the Statistical Analysis of High-Throughput RNAi Screens

Bioinformatics, Jan. 25, 2009; epub ahead of print
Kaderali et al.


Gene Regulation with Polyvalent siRNA-Nanoparticle Conjugates

Journal of the American Chemical Society, Jan. 26, 2008; epub ahead of print
Mirkin et al.


Essential and Overlapping Functions for Mammalian Argonautes in microRNA Silencing

Genes & Development, Jan. 27, 2009; epub ahead of print
Wang et al.

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Improved Retinal Function in a Mouse Model of Dominant Retinitis Pigmentosa Following AAV-Delivered Gene Therapy

Molecular Therapy, Jan. 27, 2009; epub ahead of print
Farrar et al.


Role for RNAi in the Selective Correction of DNA Methylation Defects

Science, Jan. 29, 2009; epub ahead of print
Colot et al.


Triggering the Formation of tasiRNAs in Arabadopsis thaliana: The Role of microRNA miR-173

EMBO Reports, Jan. 30, 2009; epub ahead of print
Felippes & Weigel

The Scan

Call to Look Again

More than a dozen researchers penned a letter in Science saying a previous investigation into the origin of SARS-CoV-2 did not give theories equal consideration.

Not Always Trusted

In a new poll, slightly more than half of US adults have a great deal or quite a lot of trust in the Centers for Disease Control and Prevention, the Hill reports.

Identified Decades Later

A genetic genealogy approach has identified "Christy Crystal Creek," the New York Times reports.

Science Papers Report on Splicing Enhancer, Point of Care Test for Sexual Transmitted Disease

In Science this week: a novel RNA structural element that acts as a splicing enhancer, and more.