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Products & Services: Dec 9, 2010

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Exiqon has introduced the sixth generation of its miRcury LNA microRNA arrays for the expression profiling of human, mouse, and rat miRNAs.

The new microRNA arrays have 2,361 unique capture probes covering all mature human, mouse, rat, and related viral miRNA sequences as annotated in the Wellcome Trust Sanger Institute's miRBase v16.0. The array also contains capture probes for 66 proprietary miRPlus miRNAs, the company said.


Cellecta has launched the Decipher Project, an open-source platform for genome-wide RNAi screening offering reagents for running genetic knockdown screens, software tools for data analysis, and an open database of genetic knockdown screening results.

The effort is partly funded by the National Institutes of Health and is being run with collaborators at the Fred Hutchinson Cancer Research Center, the Roswell Park Cancer Institute, and the Scripps Research Institute, Cellecta said.

Researchers from academic and non-profit institutions can obtain, at no cost, pooled lentiviral-based shRNA libraries with basic controls and access software tools for data analysis and interpretation. In exchange, they only need to agree to publicly share all genetic screen data generated after publication.

The Scan

Genetic Risk Factors for Hypertension Can Help Identify Those at Risk for Cardiovascular Disease

Genetically predicted high blood pressure risk is also associated with increased cardiovascular disease risk, a new JAMA Cardiology study says.

Circulating Tumor DNA Linked to Post-Treatment Relapse in Breast Cancer

Post-treatment detection of circulating tumor DNA may identify breast cancer patients who are more likely to relapse, a new JCO Precision Oncology study finds.

Genetics Influence Level of Depression Tied to Trauma Exposure, Study Finds

Researchers examine the interplay of trauma, genetics, and major depressive disorder in JAMA Psychiatry.

UCLA Team Reports Cost-Effective Liquid Biopsy Approach for Cancer Detection

The researchers report in Nature Communications that their liquid biopsy approach has high specificity in detecting all- and early-stage cancers.