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NEW YORK (GenomeWeb) – To overcome the challenges of limited phenotyping and bulk-cell resolution that can constrain gene function research performed using DNA barcodes, researchers at the Icahn School of Medicine at Mount Sinai have developed a barcoding system operating at the protein level. And by pairing each protein barcode with a different CRISPR guide RNA, they were able to achieve simultaneous high-dimensional protein-level phenotyping of hundreds of genes with single-cell resolution.

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Aug
28
Sponsored by
Horizon Discovery

This webinar will provide an overview of alternatives to the popular Cas9 nuclease used in CRISPR gene editing.

Oct
23
Sponsored by
Swift Biosciences

This webinar will illustrate how single-cell methylation sequencing can be applied to gain significant insight into epigenetic heterogeneity in disease states, advancing cancer research discoveries.