NEW YORK (GenomeWeb) – In the last half-year, two of the hottest trends in life science, optogenetics and CRISPR, have finally come together. Labs around the world have published papers showing light-activated Cas9 enzyme activity, which could create more powerful research tools and help nudge the technology closer to in vivo use.

The new techniques can allow either gene editing or activation and they all afford some measure of spatial or temporal control over the Cas9 enzyme.

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An opinion piece in the Guardian argues that President Donald Trump is uninterested in science and that might not be a bad thing for the field.

The San Francisco Chronicle reports the Veterans Affairs Health System is studying whether genetic testing can help prescribe better depression therapies.

Stat News reports that Spark Therapeutics' Luxturna is now being used to treat a wider array of patients.

In Genome Biology this week: transcription factor use among brittle stars, single-cell RNA sequencing strategy, and more.

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