NEW YORK (GenomeWeb) – In the last half-year, two of the hottest trends in life science, optogenetics and CRISPR, have finally come together. Labs around the world have published papers showing light-activated Cas9 enzyme activity, which could create more powerful research tools and help nudge the technology closer to in vivo use.

The new techniques can allow either gene editing or activation and they all afford some measure of spatial or temporal control over the Cas9 enzyme.

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The Chan Zuckerberg Initiative is investing in Cold Spring Harbor Laboratory's BioRxiv.

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