NEW YORK (GenomeWeb) – A team from Harvard Medical School this week published the details of a novel approach to drug-target screening, combining the genome-editing technology CRISPR and the gene-silencing technology RNAi to identify three genes that appear to be essential to the growth of tumor cells but not normal cells.

According to the researchers, the method offers a number of advantages over conventional RNAi screening, which is limited by incomplete transfection, partial knockdown, and off-target effects, and therefore often requires secondary screening.

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Sometimes genetic tests give inconclusive results and provide little reassurance to patients, the Associated Press reports.

Vox wonders whether gene-editing crops will be viewed similarly as genetically modified organisms of if people will give them a try.

In Science this week: research regulation and reporting requirement reform, and more.

With H3Africa, Charles Rotimi has been working to bolster the representation of African participants and African researchers in genomics, Newsweek reports.

Aug
07
Sponsored by
Qiagen

This webinar will present the results of an evaluation of a web-based variant interpretation software system for clinical next-generation sequencing.