NEW YORK (GenomeWeb) – A new algorithm for calculating on-target guide RNA efficiency is taking off in the field, both in home-grown and commercial CRISPR/Cas9 experiment design software.

The fruit of a collaboration between scientists at the Broad Institute and machine learning experts at Microsoft Research, the algorithm has uncovered new rules and considerations for how well a single guide RNA (sgRNA) will work for gene knock-down experiments, with results that can be broadly applied.

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Two researchers have found that behavioral genetic defenses in criminal cases don't tend to affect outcomes, according to Popular Science.

Researchers report that while host genetics influence the oral microbiome, they don't appear to affect cavity-causing microbes, the Economist says.

Pandas' gut microbiomes change as what they eat changes with the seasons, writes Discover's Inkfish blog.

In PLOS this week: comparative genomic study of malaria-linked macaque parasite, search for apple root reference genes, and more.