NEW YORK (GenomeWeb) – Scientists are using CRISPR/Cas9 genome editing to record a cell's history in its own DNA, answering questions such as where the cell came from in development, also known as cell lineage tracing, and what biochemical events it has encountered during its lifespan.

To trace cell lineage in early vertebrate development, Jay Shendure of the University of Washington and Alexander Schier of Harvard University led a team that created arrays of synthetic targets in the genome that could pick up different edits as the cells underwent ongoing rounds of division.

Get the full story with
GenomeWeb Premium

Only $95 for the
first 90 days*

GenomeWeb Premium gives you:
✔ Full site access
✔ Interest-based email alerts
✔ Access to archives

Never miss another important industry story.

Try GenomeWeb Premium now.

You may already have institutional access!

Check if I qualify.

Already a GenomeWeb or 360Dx Premium member?
Login Now.

*Before your trial expires, we’ll put together a custom quote with your long-term premium options.

Not ready for premium?

Register for Free Content
You can still register for access to our free content.

Reuters reports that UK researchers are using gene-editing tools to develop flu-resistant chickens.

Vox explores a proposal to institute a lottery system to award grant funds.

In Genome Biology this week: gut microbiome study of individuals from Tanzania and Botswana, sixth version of the Network of Cancer Genes database, and more.

Chinese state news agency Xinhua reports that a preliminary investigation has found He Jiankui performed his gene-editing work illegally.

Feb
21
Sponsored by
L7 Informatics

This webinar will provide a first-hand look at how Gradalis, a clinical-stage immunotherapy developer, is using an information management solution from L7 to streamline its research, clinical, and manufacturing operations.