NEW YORK (GenomeWeb) – A team led by researchers at the University of California, Berkeley and the University of California, San Francisco used CRISPR activation (CRISPRa) to identify enhancers of a gene that affects development of T cells, and thereby elucidate the occurrence of autoimmune disorders such as inflammatory bowel disease (IBD) and Crohn's disease.

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Microsoft co-founder Paul Allen also contributed to brain research, NPR reports.

The New York Times reports on the shifting interpretations of what some genetic variants mean over time.

In Cell this week: investigation of metastatic tumor evolution, more than 16,000 genetic variants introduced into the budding yeast model organism, and more.

MIT's Technology Review reports on Genentech's pursuit of personalized cancer vaccines.

Nov
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With the Next Generation Sequencing (NGS), genomes sequencing has been democratized over the last decades with the detection of genomic alterations, thus replacing Sanger sequencing.