CRISPRa Method Identifies Gene Enhancers Affecting T Cell Development

NEW YORK (GenomeWeb) – A team led by researchers at the University of California, Berkeley and the University of California, San Francisco used CRISPR activation (CRISPRa) to identify enhancers of a gene that affects development of T cells, and thereby elucidate the occurrence of autoimmune disorders such as inflammatory bowel disease (IBD) and Crohn's disease.