NEW YORK (GenomeWeb) – The Cas9 enzyme is known to have certain problems with binding to off-target DNA sequences, but for the most part, it is still considered to be the gold standard CRISPR enzyme for genome editing.

However, in a new study in Molecular Cell today, researchers from the University of Texas at Austin suggested that the Cas12a enzyme — previously known as Cpf1 — is more precise than Cas9 and could lead to gene editing that's safe enough to be used in humans.

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