NEW YORK (GenomeWeb) – In a study published online in Science Advances today, researchers from the Massachusetts Institute of Technology described a previously uncharacterized Cas9 ortholog from Streptococcus canis (ScCas9) which has fewer protospacer adjacent motif (PAM) requirements than the more widely used S. pyogenes Cas9 (SpCas9) and is therefore able to target more locations on the genome and more disease-causing mutations.

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