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NEW YORK (GenomeWeb) – In a study published today in Nature Biotechnology, researchers in Keith Joung's lab at Massachusetts General Hospital described their efforts to engineer enhanced variants of the Cas12a nuclease that can target a wider range of protospacer adjacent motifs (PAM), have enhanced editing activity, and have reduced off-target effects.

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US National Institutes of Health Director Francis Collins says he will avoid male-only speaker panels.

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Technology Review reports that eGenesis is testing whether organs from genetically modified pigs can be transplanted into monkeys.

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