NEW YORK (GenomeWeb) – A team led by researchers at the University of California, San Francisco used CRISPR interference (CRISPRi) to map genetic interactions in human cells at a large scale.

As they wrote yesterday in Cell, yeast studies have shown that comprehensively mapping genetic interactions (GIs) can help investigators infer gene function. However, until this point, it has not been feasible to generate large-scale, diverse human GI maps.

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