NEW YORK (GenomeWeb) – A new study published today in Nature Biotechnology shows that on-target editing by CRISPR-Cas9 can result in large deletions and complex genomic rearrangements that extend over many kilobases in the genome, and that this genomic damage may be pathogenic.

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 Senator Lamar Alexander (R-Tenn.), who chairs the Senate health committee, will be retiring at the end of his term, Stat News reports.

UCSF researchers find that having two X chromosomes may contribute to women's longer lifespans, according to Discover's D-brief blog.

The Wall Street Journal reports on the US Centers for Disease Control and Prevention's use of genetic approaches to study foodborne illnesses.

In PNAS this week: immune cell profiling of wild baboons by social status, metabolomics profiling of esophageal tumors, and more.