NEW YORK (GenomeWeb) – For scientists looking to induce targeted gene expression, a trio of CRISPR/Cas9-based activation systems stand above the rest, according to a study published today.

The VP64-p65-Rta activator (VPR, pronounced "viper), synergistic activation mediators (SAM), and the SunTag peptide array "are all pretty good choices," Marcelle Tuttle, a post-graduate fellow at the Wyss Institute for Biologically Inspired Engineering told GenomeWeb. The three technologies are all based on a nuclease-null Cas9 enzyme (dCas9) fused to proteins help that promote gene expression.

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A federal grand jury has indicted Elizabeth Holmes and Ramesh Balwani for alleged wire fraud in conjunction with their activities at Theranos.

Nature News reports that some developers are nervous about GitHub's acquisition by Microsoft.

A direct-to-consumer genetic testing company sent out used spit kits, CNBC reports.

In PLOS this week: comparison of commercial bisulfite kits, new method to predict essential proteins, and more

Jul
19
Sponsored by
Thermo Fisher Scientific

This webinar will discuss how ultra-highly sensitive and customizable targeted next-generation sequencing panels are applied in inherited disease research.