Chemically Induced Guide RNAs Drive CRISPR/Cas9 System for Editing Mouse Neurons In Vivo

Sep 29, 2016

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NEW YORK (GenomeWeb) – A new CRISPR/Cas9 system designed for editing mouse neurons in vivo uses chemically induced guide RNAs (gRNAs) to help control where and when editing happens.

The virally delivered, doxycycline-inducible system will help University of Texas at Dallas researcher Jonathan Ploski study genes associated with learning and memory in the mouse model. Last month, a Ploski-led team published a study describing it in Frontiers in Molecular Neuroscience.

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