NEW YORK (GenomeWeb) – Broad Institute researcher David Liu and his colleagues have developed a Cas9 variant that is capable of recognizing a broader range of protospacer adjacent motif (PAM) sequences than the most commonly used Cas9 from Streptococcus pyogenes (SpCas9), while also achieving greater DNA specificity and substantially lower genome-wide off-target activity.

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What happens to scientific papers when certain journals are no longer published? Some scientists are trying to make sure they don't disappear forever.

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In Genome Research this week, mismatch repair deficiency in C. elegans, retracing transcriptions start site evolution in the human genome, and more. 

May
08
Sponsored by
Dovetail Genomics

This webinar will discuss a proximity ligation-based method for studying structural variation in formalin-fixed paraffin-embedded (FFPE) tissue.