NEW YORK (GenomeWeb) – Broad Institute researcher David Liu and his colleagues have developed a Cas9 variant that is capable of recognizing a broader range of protospacer adjacent motif (PAM) sequences than the most commonly used Cas9 from Streptococcus pyogenes (SpCas9), while also achieving greater DNA specificity and substantially lower genome-wide off-target activity.

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Cancer researcher Alan Rabson has died at 92, the New York Times reports.

As the National Guideline Clearinghouse goes dark, the ECRI Institute says it will pick up the slack.

In Genome Research this week: sequencing method examines proteins parasite uses to evade immune system, L1 insertions in cancer, and more.

The Atlantic reports on private Facebook support groups for people who receive unexpected parentage results from direct-to-consumer genetic tests.

Jul
19
Sponsored by
Thermo Fisher Scientific

This webinar will discuss how ultra-highly sensitive and customizable targeted next-generation sequencing panels are applied in inherited disease research. 

Aug
07
Sponsored by
Qiagen

This webinar will present the results of an evaluation of a web-based variant interpretation software system for clinical next-generation sequencing.