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Gene Silencing/Gene Editing

News on CRISPR, gene editing, RNAi in genetics, genomics, and molecular diagnostics.

The researchers achieved RNA-guided gene editing in multiple human cell lines with high specificity and efficiencies of up to 50 percent.

The system uses chemical epigenetic modifiers to activate the expression of target genes by recruiting an endogenous chromatin-activating machinery.

Two new grants are helping the company develop its SHERLOCK and INSPECTR technologies as the basis for creating innovative diagnostics.

The company's platform is based on nucleotide deamination, a process that occurs naturally in cells and doesn't create a permanent edit in the genome.

The collaborators hope to establish new models of human disease using patient-derived stem cells, with support from Bloomberg Philanthropies.

A UK woman is suing three National Health Service Trusts for not telling her about her father's Huntington's disease diagnosis, the BBC reports.

LiveScience reports that a novel mutation in the LPL gene was uncovered in three siblings with very high triglyceride levels.

The president of Nankai University is embroiled in a data manipulation scandal, the South China Morning Post reports.

In PNAS this week: cytotoxic CD4 T cell signature in supercentenarians, evolutionary history of beetles, and more.