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Gene Silencing/Gene Editing

News on CRISPR, gene editing, RNAi in genetics, genomics, and molecular diagnostics.

Researchers Develop CRISPR Method for Dose-Dependent Gene Expression Activation

The system uses chemical epigenetic modifiers to activate the expression of target genes by recruiting an endogenous chromatin-activating machinery.

Sherlock Biosciences Aims to Create Dx Tool for 'Where Testing Should be Done, But Isn't'

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Two new grants are helping the company develop its SHERLOCK and INSPECTR technologies as the basis for creating innovative diagnostics.

Biotech Startup Korro Bio Uses Temporary Gene Editing Technology to Create Therapeutics

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The company's platform is based on nucleotide deamination, a process that occurs naturally in cells and doesn't create a permanent edit in the genome.

Johns Hopkins, NYSCF Collaborate on Stem Cell Models of Disease for Precision Medicine

The collaborators hope to establish new models of human disease using patient-derived stem cells, with support from Bloomberg Philanthropies.

Broad Institute's New Prime Editing Tech Corrects Nearly 90 Percent of Human Pathogenic Variants

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The prime editing technique has strengths that are complementary to nuclease-based editing and base editing.

Oct 10, 2019

Broad Institute Researchers Develop CRISPR-Based Diagnostic, Antiviral Platform

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Oct 10, 2019

Omics Tools Firms See Opportunities in Burgeoning Synthetic Biology Industry

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Sep 25, 2019

Chinese Biotech Startup Looks to Develop CRISPR-Based TB Diagnostic

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Sep 23, 2019

Class 1 CRISPR-Cas Systems Can Be Expressed in Mammalian Cells, Study Finds

Sep 19, 2019

Ginkgo Bioworks Raises $290M in Series E Financing

Sep 16, 2019

Alzheimer's Disease Test Firm DiamiR Awarded Additional $345K From NIA

Sep 16, 2019

Horizon Discovery Revenues Up 14 Percent in H1

Sep 06, 2019

Cardea Bio, Nanosens Launch Early-Access Program for Genome Sensor CRISPR-Chip

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Sep 06, 2019

CRISPR-Chip Makers Cardea Bio, Nanosens Agree to Merge

Sep 03, 2019

CRISPR Researchers Observe Self-Editing Activity in DNA Base Editors

Aug 30, 2019

CRISPR-Chip Shows Potential for Disease Dx, Agricultural, Research Applications

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Aug 29, 2019

Baylor, Arizona State University Nab $1.6M NIH Grant to Develop Genome Editing Governance

Aug 28, 2019

CRISPR Researchers Develop First In Vivo Editing System Targeting Non-Coding DNA

Aug 22, 2019

Single-Base Editing Expands Possibilities for Computing With DNA in Cells

Aug 15, 2019

NIH, UCSF Researchers Develop CRISPRi Platform for Genetic Screening of Human Neurons

Aug 15, 2019

Germline Genome Editing Governance Weighed by International Commission

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Aug 12, 2019

CRISPR Researchers Use Cas12a to Develop Multiplex Genome Engineering Platform

Aug 08, 2019

Dominant-Negative Effect Detected for Missense TP53 Mutations in Myeloid Cancers

Aug 01, 2019

CRISPR Patent Fight Turns Ugly as UC Accuses Broad Researchers of Lying About Claims

Jul 31, 2019

CRISPR Patent Pools Pop Up, But Participation Uncertain as IP Holders Continue Legal Battles

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The Scan

Google's Health Info Gathering

Google's Project Nightingale has collected health information on millions of Americans, according to the Wall Street Journal.

Against the Plan

An opinion piece at The Hill criticizes the proposed plan to collect DNA samples from migrants at the US border.

'Bias Throughout the Pipeline'

Nature News writes that women in chemistry are less likely to have their manuscripts accepted for publication.

PNAS Papers Explore tRNA Fragment Signature in CLL, UV Hypermutated Melanocyte Sites, More

In PNAS this week: tRNA fragment signature for chronic lymphocytic leukemia, genomic sites sensitive to ultraviolet radiation in melanocytes, and more.

Nov
13
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  1. Researchers Develop CRISPR Method for Dose-Dependent Gene Expression Activation

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