Gene Silencing/Gene Editing

News on CRISPR, gene editing, RNAi in genetics, genomics, and molecular diagnostics.

A systematic analysis of CRISPR genome editing at nearly 1,500 target sites has yielded some patterns that could make genome editing more precise.

The pharma and biotech company said it plans to use the genome editing technology in its bioproduction products and services and in stem cells for research.

The method, called negative enrichment, protects DNA regions of interest prior to degrading the surrounding DNA, making the target fragments easier to read. 

As they dig into the data on He Jiankui's genome editing experiment, CRISPR researchers say the work he did raises many scientific questions.

The 9p21.3 locus influences the expression of other genes, and affects cell adhesion and contractile force of vascular smooth muscle cells.

A genomic analysis of modern and ancient maize reveals a complicated domestication history, according to Reuters.

In PLOS this week: MYRF variant linked to congenital diaphragmatic hernia, analysis of the "dragon's blood" red resin produced by traditional medicine plants, and more.

CNBC reports that half of academic researchers leave after about five years.

Researchers have used genetic analysis to confirm a new type of salamander, the New York Times reports.