Gene Editing, Gene Silencing, & CRISPR
News on CRISPR, gene editing, RNAi in genetics, genomics, and molecular diagnostics.
GenScript Licenses Broad Institute Prime Editing Tech
Prime editing involves directly writing new genetic information into a specified DNA site and was developed at the Broad Institute.
Church, Shendure Labs Team up to Probe Possibilities for Structural Variants in Mammalian Genomes
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The authors of two newly published papers likened their method to Perturb-seq, except that it introduces structural variants instead of gene knockouts.
Colossal Biosciences Raises $200M in Series C Round
The company will use the money raised to continue advancing its genetic engineering technologies and develop new tools for applications beyond de-extinction.
BRCA2 Variants Classified in Saturation Genome Editing Studies
Research teams relied on CRISPR-Cas9-based editing and sequencing to perform high-throughput function evaluations of loss-of-function variants in exons 15 to 26 of BRCA2.
'Evo' AI Tool Trained to Model, Design Prokaryotic Genomes
After training a model called Evo with prokaryote genomes and phage sequences, researchers demonstrated its ability to predict sequence effects and generate new sequences.