Gene Silencing/Gene Editing

News on CRISPR, gene editing, RNAi in genetics, genomics, and molecular diagnostics.

The automated, whole-genome directional genomic hybridization system can measure de novo random, low-frequency, and complex structural variations.

The Suzhou, China-based company is developing medicines and molecular diagnostics based on its gene editing and delivery technologies.

The researchers showed that Cas12a discriminates strongly against mismatches to DNA targets, leading to less off-target DNA cleavage than with Cas9.

The system, called EvolvR, can continuously diversify all nucleotides within a tunable window at user-defined loci using CRISPR-guided nickases.

The teams, from the Chinese Academy of Sciences and NYU Langone Health, generated viable yeast strains with just one or two chromosomes.

In Science this week: International Wheat Genome Sequencing Consortium publishes the bread wheat cultivar Chinese Spring reference genome, and more.

At his FDA Law Blog, Jeffrey Gibbs discusses FDA's technical assistance for the draft Diagnostic Accuracy and Innovation Act.

The New York Times reports that genetic testing has uncovered unfaithful penguins at a Utah aquarium.

Cancer researcher loses funding under new Wellcome Trust anti-bullying policies, the Guardian reports.