Engineering a Different Kind of Drug Development | GenomeWeb

Using recombinant DNA technology to produce drugs in simple organisms like bacteria and yeast is nothing new. Animal-derived insulin was phased out in the early 1980s when Eli Lilly offered the first insulin drug created using recombinant techniques. Using an expression vector for the protein and injecting it into mammalian cells allowed for cheaper, more reproducible production of drugs. Other examples include erythropoietin, interferon, and the anti-Her2 monoclonal antibody.

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The White House has created a list of cuts, including to the NIH, that could be in a budget bill for this year.

The US National Institutes of Health is to allow applicants to cite preprints just as they would any other research paper, ScienceInsider reports.

Two manuscript pages handwritten by Charles Darwin are going on the auction block, according to the Los Angeles Times.

In PNAS this week: tool to track transcriptome-wide binding, evidence of balancing selection on behavior-linked genes, and more.