Gene Expression Research

The latest news about RNA-seq, gene expression profiling, and transcriptome sequencing.

The company hopes to launch its first clinical cancer test within the next year, after spending the last several years conducting validation studies.

Using the method, the researchers predicted the effects of over 140 million mutations in different tissues and identified mutations possibly associated with increased risk of several immune diseases.

Using Cancer Genome Atlas data, the researchers identified about 1,100 genes in a range of cancer types whose expression is disrupted by structural variants.

The technique features sequencing-by-ligation and error-correction strategies, and was used to simultaneously map more than 1,000 genes in mouse brain tissue.

The approach, published this week in Cell Reports, could be used more generally to discover disease genes in other cancer types.